An Agent-based Model for the Pattern Formation in Drosophila Melanogaster

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Sara Montagna, Nicola Donati, Andrea Omicini
Harold Fellermann, Mark Dörr, Martin M. Hanczyc, Lone Ladegaard Laursen, Sarah Maurer, Daniel Merkle, Pierre-Alain Monnard, Kasper Stoy, Steen Rasmussen (a cura di)
Artificial Life XII, capitolo 21, pp. 110–117
The MIT Press, Cambridge, MA, USA
agosto 2010

The hierarchical organisation of biological systems plays a crucial role in the pattern formation of gene expression resulting from the morphogenetic processes. Being able to reproduce the systems dynamics at different levels of such a hierarchy might be very useful for studying such a complex phenomenon of self-organisation. In this paper we propose the adoption of the agent-based model as an approach capable of capture multi-level dynamics.
We then realise an agent-based model of ~Drosophila Melanogaster~ morphogenesis demonstrating its capability of reproducing the expression pattern of the embryo. 

progetto finanziatore
wrench NETSCALE — Ricostruzione e modellazione delle dinamiche molecolari e genetiche alla base della precoce regionalizzazione degli embrioni di zebrafish e di seaurchin (01/07/2008–30/06/2010)