It is time for agent-based modelling (ABM) to go beyond the "me too" stage, and finally deliver up to its promises.
To this end, agent-based techniques should be tested against scenarios that have proven to be too complex for traditional approaches. In this paper, we take a complex problem in the biological domain lineage commitment of Hematopoietic Stem Cells (HSC) , and introduce an articulated agent-based model accounting for both intra- and inter-cellular aspects.
An implementation of the model in MASON is presented, and the first simulation results are discussed.
