Computational challenges in cell simulation: a software engineering approach

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Kouichi Takahashi, Katsuyuki Yugi, Kenta Hashimoto, Yohei Yamada, Christopher J.F. Pickett, Masaru Tomita
IEEE Intelligent Systems 17(5), pages 64-71
2002

Molecular biology?s advent in the 20th century has exponentially increased our knowledge about the inner workings of life. We have dozens of completed genomes and an array of high-throughput methods to characterize gene encodings and gene product operation. The question now is how we will assemble the various pieces.