Multi-Agent Systems (MAS) and Event-Based Systems (EBS) are two fundamental paradigms for the engineering of complex software systems. In this talk, we summarise the most important features of the MAS and EBS, and discuss how they could be integrated within a unified conceptual framework. The resulting framework could work as the foundation of a principled discipline for the engineering of complex software systems, by promoting a coherent integration of agent-based and event-based abstractions, languages, technologies, and methods.