Modelling Hematopoietic Stem Cell Behaviour: An Approach Based on Multi-Agent Systems


Sara Montagna, Andrea Omicini, Alessandro Ricci, Mark d'Inverno

2nd Conference "Foundations of Systems Biology in Engineering" (FOSBE 2007), pages 243-248
9-12 September 2007
Fraunhofer IBR Verlag, Stuttgart, Germany
Frank Allgöwer, Matthias Reuss (eds.)

The study of the hematopoietic system raises some fundamental issues about the regulation mechanisms that control the overall production of terminally differentiated blood cells. To address such issues, it is our view that both inter- and intra- cellular dynamics have to be considered. The macro-level self-organisation of the hematopoietic system emerges from the local micro-level interactions of its components. Following such premises, in this paper we propose a novel approach for modelling hematopoietic stem cells behaviour based on multi-agent systems. The adoption of this paradigm allows to take into account the aspects suggested above, explicitly modelling cell internal behaviour, the environment where they are situated and the interaction between the system entities.

 @inproceedings{sysbio-fosbe07,
Address = {Stuttgart, Germany},
Author = {Montagna, Sara and Omicini, Andrea and Ricci, Alessandro and d'Inverno, Mark},
Booktitle = {2nd Conference ``Foundations of Systems Biology in Engineering'' (FOSBE 2007)},
Editor = {Allg{\"o}wer, Frank and Reuss, Matthias},
Isbn = {978-3-8167-7436-5},
Month = {9--12~} # sep,
Pages = {243--248},
Publisher = {Fraunhofer IBR Verlag},
Title = {Modelling Hematopoietic Stem Cell Behaviour: An Approach Based on Multi-Agent Systems},
Year = 2007

Publication

— authors

Sara Montagna, Andrea Omicini, Alessandro Ricci, Mark d'Inverno

— editors

Frank Allgöwer, Matthias Reuss

— status

published

— sort

paper in proceedings

Venue

— volume

2nd Conference "Foundations of Systems Biology in Engineering" (FOSBE 2007)

— pages

243-248

— context

2nd Conference “Foundations of Systems Biology in Engineering” (FOSBE 2007)

— where

Stuttgart, Germany

— publication date

9-12 September 2007

Identifiers

— print ISBN

978-3-8167-7436-5

BibTeX

— BibTeX ID
sysbio-fosbe07
— BibTeX category
inproceedings

Partita IVA: 01131710376 - Copyright © 2008-2022 APICe@DISI Research Group - PRIVACY