A Process Model of Rho GTP-binding Proteins in the Context of Phagocytosis


Luca Cardelli, Philippa Gardner, Ozan Kahramanoğulları

Proceedings of the First Workshop "From Biology To Concurrency and back (FBTC 2007)", pages 87102
Electronic Notes in Theoretical Computer Science 194(3),  2008
Elsevier Science Publishers B. V., Amsterdam, The Netherlands, The Netherlands

At the early stages of the phagocytic signalling, Rho GTP-binding proteins play a key role. With the stimulus from the cell membrane and with the help from the regulators (GEF, GAP, Effector, GDI), these proteins serve as switches that interact with their environment in a complex manner. We present a generic process model for the Rho GTP-binding proteins, and compare it with a previous model that uses ordinary differential equations. We then extend the basic model to include the behaviour of the GDIs. We discuss the challenges this extension brings and directions of further research.

 @article{rhogtpmodel-entcs08,
author = {Cardelli, Luca and Gardner, Philippa and Kahramanogullari, Ozan},
title = {A Process Model of Rho GTP-binding Proteins in the Context of Phagocytosis},
journal = {Electronic Notes in Theoretical Computer Science},
volume = 194,
number = 3,
year = 2008,
issn = {1571-0661},
pages = {87--102},
doi = {http://dx.doi.org/10.1016/j.entcs.2007.12.007},
publisher = {Elsevier Science Publishers B. V.},
address = {Amsterdam, The Netherlands, The Netherlands},
 } 

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Publication

— authors

Luca Cardelli, Philippa Gardner, Ozan Kahramanoğulları

— status

published

— sort

paper in proceedings

Venue

— volume

Proceedings of the First Workshop "From Biology To Concurrency and back (FBTC 2007)"

— series

Electronic Notes in Theoretical Computer Science

— volume

194

— issue

3

— pages

87102

— publication date

2008

URLs

original PDF

Identifiers

— DOI

10.1016/j.entcs.2007.12.007

— print ISSN

1571-0661

BibTeX

— BibTeX ID
rhogtpmodel-entcs08
— BibTeX category
article

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