In order for multiagent systems to be included in real domains (media and Internet, logistics, e-commerce, and health care), infrastructures and tools for multiagent systems should provide efficiency, scalability, security, management, monitoring, and other features related to building real applications. Thus, infrastructures and tools that support multiagent systems are needed, especially those that promote the adoption of agent-based systems by designers and programmers in both academia and industry. This special issue is a selection of contributions whose preliminary versions were presented at the ITMAS 2010 workshop, which was held in conjunction with the International Conference on Autonomous Agents and Multi-agent Systems.