Sara Montagna, Alessandro Ricci, Andrea Omicini

Multiagent systems (MASs) are seemingly a promising way to model and simulate biological systems and networks, going toward a system-level understanding of such complex systems, as promoted by Systems Biology. In this paper we propose an agent-based framework based on the notion of agents and artifacts, implemented on top of the TuCSoN agent coordination model and infrastructure. The approach promotes the engineering of distributed simulations, where biological networks are modelled as multiagent systems. There, agents — representing active biological components such as proteins and enzymes — interact by means of tuple centres — representing the environment that enables and mediates the interaction of such components.

Industrial Simulation Conference 2006 (ISC 2006), pages 25-32, 5-7 June 2006.
Alessandro Genco, Antonio Gentile, Salvatore Sorce (eds.), Palermo, Italy

@inproceedings{biosim-isc06,
	Address = {Palermo, Italy},
	Author = {Montagna, Sara and Ricci, Alessandro and Omicini, Andrea},
	Booktitle = {Industrial Simulation Conference 2006 (ISC 2006)},
	Editor = {Genco, Alessandro and Gentile, Antonio and Sorce, Salvatore},
	Isbn = {90-77381-26-0},
	Month = {5--7~} # jun,
	Organization = {EUROSIS (The European Simulation Society) \& ETI (The European Technology Institute)},
	Pages = {25--32},
	ScopusId = {2-s2.0-84898461989},
	Title = {Agents \& {A}rtifacts for {S}ystems {B}iology: Toward a Framework based on {{\sf TuCSoN}}},
	WosId = {000245531000004},
	Year = 2006}