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An Agent-based Model for the Pattern Formation in Drosophila Melanogaster

Sara Montagna, Nicola Donati, Andrea Omicini
The hierarchical organisation of biological systems plays a crucial role in the pattern formation of gene expression resulting from the morphogenetic processes. Being able to reproduce the systems dynamics at different levels of such a hierarchy might be very useful for studying such a complex phenomenon of self-organisation. In this paper we propose the adoption of the agent-based model as an approach capable of capture multi-level dynamics. We then realise an agent-based model of Drosophila Melanogaster morphogenesis demonstrating its capability of reproducing the expression pattern of the embryo.
Artificial Life XII, Ch. 21, pages 110-117, 19-23 August 2010.
Harold Fellermann, Mark Dörr, Martin M. Hanczyc, Lone Ladegaard Laursen, Sarah Maurer, Daniel Merkle, Pierre-Alain Monnard, Kasper Stoy, Steen Rasmussen (eds.), The MIT Press, Cambridge, MA, USA
Proceedings of the 12th International Conference on the Synthesis and Simulation of Living Systems, 19-23 August 2010, Odense, Denmark 
@incollection{abmmorpho-alifexii,
	Address = {Cambridge, MA, USA},
	Author = {Montagna, Sara and Donati, Nicola and Omicini, Andrea},
	Booktitle = {Artificial Life XII},
	Chapter = 21,
	Editor = {Fellermann, Harold and D{\"o}rr, Mark and Hanczyc, Martin M. and Ladegaard Laursen, Lone and Maurer, Sarah and Merkle, Daniel and Monnard, Pierre-Alain and Stoy, Kasper and Rasmussen, Steen},
	Isbn = {978-0-262-29075-3},
	Isbn-10 = {0-262-29075-8},
	Note = {Proceedings of the 12th International Conference on the Synthesis and Simulation of Living Systems, 19-23~} # aug # {~2010, Odense, Denmark},
	Pages = {110--117},
	Pdf-Url = {http://mitpress.mit.edu/sites/default/files/titles/alife/0262290758chap21.pdf},
	Publisher = {The MIT Press},
	ScopusId = {2-s2.0-83155172118},
	Title = {An Agent-based Model for the Pattern Formation in {D}rosophila {M}elanogaster},
	Year = 2010}