Lineage Commitment of Hematopoietic Stem Cells: An Agent-based Model


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Sara Montagna, Andrea Omicini, Marco Alberti

Giuliano Armano, Marco Schaerf, Giovanni Semeraro (a cura di)
“Intelligenza Artificiale e Scienze della Vita”, pp. 201-214
settembre 2008

It is time for agent-based modelling (ABM) to trespass the "me too" stage, so as to deliver up to its promises. To this end, agent-based techniques should be tested against scenarios that have proven to be too complex for traditional approaches. In this paper, we take a complex problem in the biological domain — lineage commitment of Hematopoietic Stem Cells (HSC) —, and introduce an articulated agent-based model accounting for both intra- and inter-cellular aspects. An implementation of the model in MASON is presented, and the first simulation results are discussed.

10° Convegno Associazione Italiana per l'Intelligenza Artificiale (AI*IA 2008), Workshop "Multi-agent Systems & Bioinformatics" (MAS&BIO 2008). Proceedings

Pubblicazione

— autori/autrici

— a cura di

Giuliano Armano, Marco Schaerf, Giovanni Semeraro

— stato

pubblicato

— tipo

articolo in atti

— data di pubblicazione

settembre 2008

— volume

Intelligenza Artificiale e Scienze della Vita

— pagine

201-214

— indirizzo

Cittadella dei Musei, Cagliari, Italy

identificatori

— IRIS

11585/62600

note

— nota

10° Convegno Associazione Italiana per l'Intelligenza Artificiale (AI*IA 2008), Workshop "Multi-agent Systems & Bioinformatics" (MAS&BIO 2008). Proceedings

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