Lineage Commitment of Hematopoietic Stem Cells: An Agent-based Model


pagemagnifierBibTeX_logo.pngmagnifierpage_white_acrobatmagnifier

Sara Montagna, Andrea Omicini, Marco Alberti

Giuliano Armano, Marco Schaerf, Giovanni Semeraro (eds.)
“Intelligenza Artificiale e Scienze della Vita”, pages 201-214
September 2008

It is time for agent-based modelling (ABM) to trespass the "me too" stage, so as to deliver up to its promises. To this end, agent-based techniques should be tested against scenarios that have proven to be too complex for traditional approaches. In this paper, we take a complex problem in the biological domain — lineage commitment of Hematopoietic Stem Cells (HSC) —, and introduce an articulated agent-based model accounting for both intra- and inter-cellular aspects. An implementation of the model in MASON is presented, and the first simulation results are discussed.

10° Convegno Associazione Italiana per l'Intelligenza Artificiale (AI*IA 2008), Workshop "Multi-agent Systems & Bioinformatics" (MAS&BIO 2008). Proceedings

Publication

— authors

— editors

Giuliano Armano, Marco Schaerf, Giovanni Semeraro

— status

published

— sort

paper in proceedings

— publication date

September 2008

— volume

Intelligenza Artificiale e Scienze della Vita

— pages

201-214

— address

Cittadella dei Musei, Cagliari, Italy

identifiers

— IRIS

11585/62600

notes

— note

10° Convegno Associazione Italiana per l'Intelligenza Artificiale (AI*IA 2008), Workshop "Multi-agent Systems & Bioinformatics" (MAS&BIO 2008). Proceedings

Partita IVA: 01131710376 — Copyright © 2008–2023 APICe@DISI – PRIVACY