Lineage Commitment of Hematopoietic Stem Cells: An Agent-based Model
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Giuliano Armano, Marco Schaerf, Giovanni Semeraro (eds.)
Intelligenza Artificiale e Scienze della Vita, pages 201–214
September 2008
It is time for agent-based modelling (ABM) to trespass the “me too” stage, so as to deliver up to its promises. To this end, agent-based techniques should be tested against scenarios that have proven to be too complex for traditional approaches. In this paper, we take a complex problem in the biological domain — lineage commitment of Hematopoietic Stem Cells (HSC) —, and introduce an articulated agent-based model accounting for both intra- and inter-cellular aspects. An implementation of the model in MASON is presented, and the first simulation results are discussed. |
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Giuliano Armano, Marco Schaerf, Giovanni Semeraro
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published
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September 2008
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Intelligenza Artificiale e Scienze della Vita
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201–214
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Cittadella dei Musei, Cagliari, Italy
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10° Convegno Associazione Italiana per l'Intelligenza Artificiale (AI*IA 2008), Workshop "Multi-agent Systems & Bioinformatics" (MAS&BIO 2008). Proceedings