Lineage Commitment of Hematopoietic Stem Cells: An Agent-based Model

Sara Montagna, Andrea Omicini, Marco Alberti

Giuliano Armano, Marco Schaerf, Giovanni Semeraro (eds.)
Intelligenza Artificiale e Scienze della Vita, pages 201–214
September 2008

It is time for agent-based modelling (ABM) to trespass the “me too” stage, so as to deliver up to its promises. To this end, agent-based techniques should be tested against scenarios that have proven to be too complex for traditional approaches. In this paper, we take a complex problem in the biological domain — lineage commitment of Hematopoietic Stem Cells (HSC) —, and introduce an articulated agent-based model accounting for both intra- and inter-cellular aspects. An implementation of the model in MASON is presented, and the first simulation results are discussed.


— authors

— editors

Giuliano Armano, Marco Schaerf, Giovanni Semeraro

— status


— sort

paper in proceedings

— publication date

September 2008

— volume

Intelligenza Artificiale e Scienze della Vita

— pages


— address

Cittadella dei Musei, Cagliari, Italy





— note

10° Convegno Associazione Italiana per l'Intelligenza Artificiale (AI*IA 2008), Workshop "Multi-agent Systems & Bioinformatics" (MAS&BIO 2008). Proceedings

Partita IVA: 01131710376 — Copyright © 2008–2023 APICe@DISI – PRIVACY