The fundamental turn of software into concurrency and distribution is not only a matter of performance, but also of design and abstraction. It calls for programming paradigms that, compared to current mainstream paradigms, would allow us to more naturally think about, design, develop, execute, debug, and profile systems exhibiting different degrees of concurrency, autonomy, decentralization of control, and physical distribution. The AGERE! workshop is dedicated to focusing on and developing the research on programming systems, languages and applications based on actors, agents and any related programming paradigm promoting a decentralized mindset in solving problems and in developing systems to implement such solutions. The workshop is designed to cover both the theory and the practice of design and programming, bringing together researchers working on the models, languages and technologies, and practitioners developing real-world systems and applications. The AGERE! workshop was successfully organized in SPLASH 2011 (http://agere2011.apice.unibo.it) and is proposed to be offered again at SPLASH 2012.