Talks » Lineage Commitment of Hematopoietic Stem Cells: An Agent-based Model

Lineage Commitment of Hematopoietic Stem Cells: An Agent-based Model

Andrea Omicini, Sara Montagna
It is time for agent-based modelling (ABM) to go beyond the "me too" stage, and finally deliver up to its promises. To this end, agent-based techniques should be tested against scenarios that have proven to be too complex for traditional approaches. In this paper, we take a complex problem in the biological domain -- lineage commitment of Hematopoietic Stem Cells (HSC) --, and introduce an articulated agent-based model accounting for both intra- and inter-cellular aspects. An implementation of the model in MASON is presented, and the first simulation results are discussed.

Presented by Andrea Roli
MAS&Bio'08
11/09/2008